Cholesterol Goals
Based on National
Institutes of Health
Recommendations
Total less than
Cholesterol: 200 mg/dL
LDL “Bad” less than
Cholesterol: 130 mg/dL
HDL “Good” 60 mg/dL
Cholesterol: or more
Cholesterol Goals
Based on National
Institutes of Health
Recommendations
Total less than
Cholesterol: 200 mg/dL
LDL “Bad” less than
Cholesterol: 130 mg/dL
HDL “Good” 60 mg/dL
Cholesterol: or more
Cholesterol Regulation Complex*


Helps Retain Normal Cholesterol Levels and Promotes
Cardiovascular Health*

Cholesterol Regulation
Complex is a unique
blend of natural
ingredients that helps
retain normal
cholesterol levels and
also increases HDL
“good” cholesterol
levels by up to 37%
within three months.
It helps inhibit
absorption of dietary
cholesterol and does
not interrupt coenzyme
Q10 production.
N-acetylcysteine is an
antioxidant that may
help prevent LDL
“bad” cholesterol
oxidation.*

Cholesterol
Regulation Complex*

180 tablets #20648

CHALLENGE

Every 33 seconds, an American dies of heart disease. That’s nearly a million of us a year.
Heart disease is more likely to kill you than cancer,respiratory diseases,or car accidents.
And,counter to popular opinion,heart attacks kill even more women than men.

To take a proactive approach to your own heart health,it’s important to retain normal
cholesterol levels. The National Institutes of Health and the American Heart
Association say that half of all American adults may have elevated cholesterol
(200mg/dL or higher).1 Elevated blood cholesterol doubles the risk of heart disease.
The best way to maintain heart health is to take a proactive approach by eating a
heart-healthy diet, exercising on a regular basis, and retaining normal cholesterol levels.

CHOLESTEROL REGULATION COMPLEX*

Cholesterol Regulation Complex provides a safe, natural way to promote
cardiovascular health.*

¦ Helps retain normal cholesterol levels*
¦ Increases HDL (“good”) cholesterol levels by up to 37% within three months*
¦ May help prevent LDL (“bad”) cholesterol oxidation*
¦ Helps inhibit absorption of dietary cholesterol*
¦ Does not interrupt production of coenzyme Q10,a nutrient that provides strength
and energy to the heart*
WHO WILL BENEFIT FROM CHOLESTEROL REGULATION COMPLEX*?

All men and women, ages 12 and up, who want a safe, natural way to take control

of their cholesterol levels, especially those with:
¦ A family history of heart disease or type 2 diabetes ¦ Physical inactivity
¦ Diets high in cholesterol or saturated fats ¦ Smoking
¦ Excess weight or obesity

HOW SHOULD CHOLESTEROL REGULATION COMPLEX* BE USED?


The recommended serving of Cholesterol
Regulation Complex* for adult men,
women, and young adults (ages 12 and
up) is six tablets per day in divided doses.
These can be spaced to suit individual
convenience. For example, take two each
with breakfast, lunch, and dinner, or three
with lunch and three with dinner.

If pregnant or nursing, ask a health care
professional.

WHAT’S IN CHOLESTEROL
REGULATION COMPLEX*?

¦ Hydrolyzed Soy Protein Blend
provides specially processed
phytopeptides with bound
phospholipids to inhibit the absorption
of cholesterol in the intestinal tract,
thereby helping to retain normal
cholesterol levels.*
Supplement Facts
Serving Size: 6 Tablets
Servings Per Container: 30
Amount Per Serving
Calories 15
% Daily Value
Total Carbohydrate 1 g <1%**
Protein 2 g 4%**
Sodium 60 mg 2%
Hydrolyzed Soy Protein Blend 3000 mg †
Phytopeptides with bound phospholipids
N-acetylcysteine 200 mg †
** Percent Daily Values are based on a 2,000 calorie diet.
† Daily values not established.
Other Ingredients: dicalcium phosphate,
croscarmellose sodium.
* THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION.
THIS PRODUCT IS NOT INTENDEDTO DIAGNOSE,TREAT,CURE,OR PREVENT ANY DISEASE.

¦ N-acetylcysteine (NAC), a plant-derived antioxidant,
contributes the amino acid I-cysteine, which is involved
in the body’s production of the powerful antioxidant
glutathione. Scientific evidence suggests NAC may help
prevent the oxidation of LDL (“bad”) cholesterol.*
SCIENTIFIC EVIDENCE IN SUPPORT OF THE
INGREDIENTS IN CHOLESTEROL REGULATION
COMPLEX*

¦ Several studies have shown that phytopeptides with
bound phospholipids from soy help retain normal
cholesterol levels by inhibiting the absorption of
dietary cholesterol.2,3,4
¦ Phytopeptides with bound phospholipids from soy
have been shown to increase HDL by 26% after two
months and 37% within three months.4
¦ N-acetylcysteine (NAC) has been shown to help
neutralize free radicals and protect against oxidation of
LDL cholesterol.5,6,7
¦ In vitro studies have shown N-acetylcysteine to be a
strong inhibitor of LDL oxidation.
WHY CHOOSE SHAKLEE CHOLESTEROL
REGULATION COMPLEX*?

¦ The safe, natural approach to retaining normal
cholesterol levels*
¦ Clinically proven ingredients
¦ Raises HDL levels by up to 37% in three months*
¦ Inhibits absorption of dietary cholesterol*
¦ Does not interrupt coenzyme Q10 production*
¦ 100% Shaklee Guaranteed
Clinically proven to increase
HDL (“good”) cholesterol†


†Clinical studies of the phytopeptides with bound phospholipids in
Cholesterol Regulation Complex* showed a 37% increase in HDL levels
within three months.
SUPPORT MATERIALS

Cholesterol Regulation Complex* Brochure

English #74902 Spanish #74903
May 2003 – Hotline Product Profile #65849
June 2003 – Hotline featuring a Science Talk segment on
strategies to lower your cholesterol levels #65850

* THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION.
THIS PRODUCT IS NOT INTENDEDTO DIAGNOSE,TREAT,CURE,OR PREVENT ANY DISEASE.
COMPLEMENTARY SHAKLEE PRODUCTS
FOR HEART HEALTH

CoQHeart® – Provides strength and energy to the
heart with a highly bio-available form of coenzyme Q10.*
30 capsules/30 servings #20647

Essential Omega-3 Complex – Helps optimize
cardiovascular health with omega-3 fatty acids, EPA,
DHA, and more.* 90 capsules/30 servings #20234

Vita-E Complex® – Vitamin E, selenium, and grapeseed
extract for powerful antioxidant protection. Protects
artery walls and helps prevent LDL oxidation.*
120 capsules/60 servings #20112

Shaklee Fiber Plan® Unflavored – Dietary fiber to
promote heart health and help retain normal cholesterol
levels. 11.9 oz. (337 grams)/67 servings #20362
Garlic Complex – Helps retain normal blood pressure
and cholesterol levels.*
60 tablets/30servings #20083
240 tablets/120 servings #20084

B-Complex – High-Potency B vitamins with folic acid.
Supports healthy hearts by helping to lower
homocysteine levels.
120 tablets/60 servings #20186
240 tablets/120 servings #20194

Energizing Soy Protein

Biologically complete protein with all the health benefits
of soy. Daily intake of soy protein helps retain normal
cholesterol levels and promotes heart health.*

30 oz. (850 grams)/30 servings
Vanilla #20665 Cocoa #20670

References:

1
NHLBI. National Cholesterol Education Program. High Blood
Cholesterol. NIH Publication 01–3290, 2001.

2Yamamoto S,Yeuching W,Tzu-Gsiu C, Hori G, Morishita K,
Kamiya S, Matsuoka K,Yamamoto K, Nagaoka S. The effect of
soybean-protein hydolyzate with bound phospholipids on
serum lipid levels in adult male hypercholesterolemic subjects.
Health Nutrition Food Research,1 3/4:1-8 1998.

3
Hori G,Yamamoto K,Kamiya T,Hara T,Nagaoka S,Motoya N,
Yamamoto S. The effect of soybean protein hydrolyzate with
bound phospholipids on serum cholesterol levels in adult male
subjects receiving high cholesterol diet. Japanese Society of
Clinical Nutrition, 22 3:21–27, 2000.

4
Hori G et al. Soy protein hydrolyzate with bound phospholipids
reduces serum cholesterol levels in hypercholesterolemic adult
male volunteers. Bioscience Biotechnol Biochemical 65:72–78, 2001.

5 Dhalla NS et al. Role of oxidative stress in cardiovascular
disease. Journal of Hypertension 18:655–73, 2000.
6 Kelly GS. Clinical applications of N-acetylcysteine. Alternative
Medicine Rev 3:114–27, 1998.

7
Hultberg B et al. Plasma homocysteine and thiol compound
fractions after oral administration of N-acetylcysteine. Scand J
Clinical Lab Invest 54:417–22, 1994.

If for any reason a Shaklee product is not
satisfactory, return it to your Shaklee
Independent Distributor or Shaklee
Corporation for exchange or a full refund.


For more information, visit www.shaklee.com.

©2003 Shaklee Corporation
Distributed by: Shaklee U.S., Inc., Pleasanton, CA 94588 03-143 (New 4/03)